Check out with all your wellbeing care Skilled if any of the following Unwanted side effects continue or are bothersome or In case you have any questions on them:
Getting notes and sharing them with all your medical doctor should help them learn more regarding how Provigil affects you. They will then use this information and facts to regulate your therapy strategy if desired.
This is not an entire listing of achievable Unwanted effects. Should you observe other consequences not detailed earlier mentioned, Make contact with your health care provider or pharmacist.
Dose changes of those medications and various prescription drugs that are substrates for CYP2C19 may very well be required when made use of concomitantly with PROVIGIL [see Medical PHARMACOLOGY].
Drug interactions may possibly adjust how your medications perform or raise your threat for serious side effects. This document won't incorporate all attainable drug interactions.
Modafinil is additionally contraindicated in specified cardiac conditions, like uncontrolled moderate to significant hypertension, arrhythmia, cor pulmonale,[89][ninety] and in situations with indications of CNS stimulant-induced mitral valve prolapse or remaining ventricular hypertrophy.[91][ninety two] The package insert in the United States cautions about making use of modafinil in those with a documented professional medical record of remaining ventricular hypertrophy or These diagnosed with mitral valve prolapse who may have Earlier exhibited indications affiliated with the mitral valve prolapse syndrome though going through treatment involving central nervous technique stimulants.[ninety three] The explanations why modafinil is contraindicated in particular cardiac circumstances are since modafinil influences the autonomic anxious system and, especially, exerts significant effects on autonomic cardiovascular regulation, major in many people to notable will increase in heart charge and blood pressure level.
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Dosage adjustment of these medications really should be regarded when these medicines are utilised concomitantly with PROVIGIL [see Medical PHARMACOLOGY].
PROVIGIL may perhaps lead to severe Negative effects such as a serious rash or a significant allergic website reaction that may have an impact on parts of Your system like your liver or blood cells. Any of such may possibly need to be taken care of in a healthcare facility and may be existence-threatening.
Provigil can be a medication that is commonly prescribed for your therapy of sleep Problems such as narcolepsy, obstructive sleep apnea, and change do the job slumber condition. It is usually from time to time employed off-label to take care of problems like notice deficit hyperactivity dysfunction and fatigue affiliated with a number of sclerosis.
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Table one provides the adverse reactions that occurred in a charge of one% or more and were additional Regular in PROVIGIL-treated people than in placebo-taken care of patients during the placebo-controlled clinical trials.
From postmarketing working experience, there are already reports of deadly overdoses involving modafinil by itself or in combination with other prescription drugs. Indicators most often accompanying PROVIGIL